ceesdekker.net Secrets
ceesdekker.net Secrets
Blog Article
Maak daarom direct een free of charge account aan. Daarmee heb je ook toegang tot onze webinars. Registreren duurt minder dan een minuut en is helemaal free of charge.
1996, 1st mesoscopic cost density waves gadgets; and initial electrical measurements on just one metallic nanocluster in between nanoelectrodes
Multicolor imaging of the bacterial nucleoid and mobile division proteins with blue, orange, and in close proximity to-infrared fluorescent proteins
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and 1st ever review from the dynamics DNA supercoils and the invention of supercoil hopping
Experimental stage diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,
What distinguishes biology from chemistry is the fact these elements alongside one another make up a residing technique. The secret of stated everyday living, I believe, lies during the interactions, the interplay of Those people molecules. The big problem in regards to the origin of everyday living continues to be unanswered. How did we at any time evolve from easy molecules in the extremely advanced systems we see currently? We have no idea. I would like to operate on These types of large, open thoughts.’
Nanopores depict a chic and functional Software to evaluate solitary molecules. We exploration novel detection modes with stable-point out nanopores together with many tips on how to evaluate proteins with nanopores. Initiatives encompass the next:
2003, demonstrated the first biosensors built outside of a carbon nanotube; solved the framework and mechanism of DNA restore proteins; and discovery of a new system for fabricating stable-condition nanopores for DNA translocation
Really neat, but that wasn’t actually where by my curiosity lay. I planned to pioneer And that i had the feeling which was now not attainable, as the most fascinating fundamental insights had by now been uncovered. But my field had formulated many thrilling new instruments to evaluate individual molecules. I decided that I needed to apply this to biology, to look at it from ceesdekker.net a Actual physical point of view.’
An integrated microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
‘That considerations the artificial cell, as Section of the Dutch BaSyC initiative. Craig Venter appeared best-down in Those people days and discovered about five hundred genes that happen to be minimally required for the performing cell. We want to glimpse bottom-up: how do we go from the couple of molecules to a whole Organic system?
2005, discovery in the system of DNA uncoiling by topoisomerase enzymes; discovery of extended-vary conformational alterations in Mre11/DNA fix complexes; and to start with power measurements with a DNA molecule inside a nanopore
‘I am driven by speculate and thoughts. On a material degree I uncover responses in physics, but I experience my deepest happiness with God. That faith also drives my science And just how I manage people.